Screening for breast cancer with mammography
Brustkrebsscreening mit Mammographie
Details
| AutorIn | Gotzsche, P.C.und Nielsen, M. |
| HerausgeberIn | The Cochrane Collaboration |
| Verlag | John Wiley & Sons, Ltd |
| Erscheinungsjahr | 2006 |
| Erscheinungsort | Oxford |
| In | The Cochrane Library 2006, Issue 4 |
| Internet | Cochrane Review |
Kurzbeschreibung
"Screening likely reduces breast cancer mortality. Based on all trials, the reduction is 20%, but as the effect is lower in the highest quality trials, a more reasonable estimate is a 15% relative risk reduction. Based on the risk level of women in these trials, the absolute risk reduction was 0.05%. Screening also leads to overdiagnosis and overtreatment, with an estimated 30% increase, or an absolute risk increase of 0.5%. This means that for every 2000 women invited for screening throughout 10 years, one will have her life prolonged. In addition, 10 healthy women, who would not have been diagnosed if there had not been screening, will be diagnosed as breast cancer patients and will be treated unnecessarily. It is thus not clear whether screening does more good than harm. Women invited to screening should be fully informed of both benefits and harms."
Dies ist die ungekürzte Zusammenfassung der Ergebnisse des Cochrane Berichts.
Die Erniedrigung der Brustkrebssterblickkeit wird mit 15-20 % beziffert, je nachdem welche Maßstäbe an die Studienqualität gelegt werden. Von 2000 Frauen, die 10 Jahre lang am Screening teilnehmen, wird bei 1 Frau eine Lebensverlängerung durch die Maßnahme SCreening zu erreichen sein.
Der Volltext des Berichts kann kostenpflichtig bestellt werden.
(letzte Aktualisierung am: 15.01.2007)